Details on the five metabolites of mephedrone
Mephedrone metabolism has been the subject of in vitro and in vivo research in both animal models and humans. N-demethylation...
Health effect
Preclinical studies of mephedrone neurotoxicity and hypothermia
Along with other compounds in the class of psychostimulants, mephedrone bears a striking resemblance in structure and acute action mechanism...
Effect of individual mephedrone metabolites on monoamine transporter activity
The chemical structure of cathinones was described as far back as 1929, but the first reports of its recreational use...
Finger necrosis due to mephedrone (case report)
Mephedrone is one of the most popular synthetic cathinone derivatives used recreationally. Despite being created in 1929, the substance did...
Why does mephedrone reduce memory?
Predominantly during adolescence, many neurobiological developmental stages can be affected by various environmental factors, including drugs. Current evidence suggests that...
How mephedrone is distributed in the human body during intoxication
As known from various studies, the main enzyme responsible for the metabolism of mephedrone in humans is cytochrome P450 D6...
Mephedrone Related Fatalities: a Review
Mephedrone [4-methylmethcathinone; 4-methylephedrone; 4-MMC; UPAC: 2-(methylamino)-1-(4-methylphenyl)propan-1-one] is a class of designer drugs and is structurally similar to cathinone, which is...
Mephedrone and HCV infection: how does the liver suffer?
Back in 2016, the Lancet published an article stating that mephedrone-related deaths are on the rise in many countries, with...